Migraine Medications - The paradox of caffeine

Caffeine has a paradoxical relationship of migraine. While in relation to these common over-the-counter painkillers such as paracetamol or aspirin, is also implicated as a trigger of migraine. Many migraine sufferers, including myself, have found that caffeine alone can significantly reduce the pain of a migraine, particularly if consumed before the onset of the headache. But caffeine, which is seen as one of the most migraine medications, it is notedhave a long-term effect as a trigger. In fact, as we shall see in this article, caffeine can also be a major cause of migraine. This paradoxical relationship between the world's most popular stimulant and skull your suffering, in my opinion, deserves special attention.

If canned, probably by humans (for example, somewhere between a cup of coffee and three vessels) are taken to consume caffeine only known effect on the human body for the adenosine receptors is to blockPreventing the adenosine from attaching to these receptors. Adenosine, a neurotransmitter that occurs robust, with a large number of functions, but their primary function is to regulate the production of other neurotransmitters such as dopamine, serotonin, norepinephrine and acetylcholine. If you have not heard of these neurotransmitters happen to your body's primary means of treatment and disposal to be the sensation of pain. Even more remarkable is the fact that adenosine only will,Pain in specific areas, such as the brain stem to kill and cause pain in other areas, such as the eyes and skin.

Migrane

The prevailing wisdom is that migraine is expanding the blood vessels or oscillations are caused by blood vessels. It 'important to note that the expansion and vibration, is itself caused by something else. Among other things, the effect of adenosine on blood vessels is a suspension, while the effect of caffeine on blood vessels contract. So even if wefollow the conventional wisdom, there is already a significant relationship between caffeine, adenosine, and your headache: migraine with whether the dilation of blood vessels, and adenosine dilates the blood vessels are connected, then it is obvious that adenosine contributes somehow the pain associated with migraine. It also suggests that caffeine, adenosine acts and contracts blood vessels would help alleviate the pain.

Migraine Medications - The paradox of caffeine

It is interesting to note that migraines weredetermined to be associated with increased levels of adenosine in both the head and neck in combination. Since caffeine is known to block an effective migraine treatment, and because caffeine is only known chemical effect on adenosine receptors, it would naturally be led to believe that somehow this increase in adenosine during a migraine has a central role in the sensation of pain. Thus, while the adenosine seems to be a pain in some parts of the body where patients with migraine areare affected, it is obviously a pain-causer. Thus, the effect of caffeine blocks a fairly obvious way to reduce the pain that accompanies a migraine so famous.

So far so good, right? If you get a headache, just drink coffee and look to solve the headache. Case closed, next please!

Not so fast, friend.

Unfortunately, because caffeine is a poison nerve, your body will naturally try to accommodate their presence. Although the effect of caffeine in ato block the reception of adenosine, your body, compensating for sensitivity to adenosine. In other words, you develop multiple adenosine receptors and these receptors become more sensitive. This leads to the negative reaction known for using caffeine as a long-term treatment of migraine. Your body begins to wait for the regular dose of caffeine, and if they do not get found themselves inundated with adenosine, which is expected to be blocked by caffeine. So ourpossible cure, of course, can worsen the problem caused by changing one of its funds in one of the 'headache.

The two-edged sword aspect of caffeine suggests that a migraineur be better served by an approach of moderation, caffeine can help relieve the pain, but it helps to bring more pain than it relieves. But even if we take caffeine in moderation to undesirable neuronal adaptation: greater sensitivity ofAdenosine, decreased sensitivity to dopamine, serotonin and other neurotransmitters, the effect is similar to caffeine and adenosine in contrast. It turns out that a single cup of coffee per day (100 mg), triggers the adaptive response of the body on Caffeine: neurotransmitters that cause more pain and less pain neurotransmitters. In addition, long-term and / or heavy caffeine consumers who report an extreme sensitivity to caffeine because caffeine as a migraine at the end. In other words, for someThe people, the threshold for the body is adjusting (read: addiction) can be much less than 100 mg of caffeine per day.

So what the final cost to be both a migraineur caffeine and user? Now the studies are not conclusive. Since all studies on the effects of caffeine on headaches have not actually tested their control groups for the presence of caffeine in their diet and because these studies have allowed the subjects to report their diet, it is very likely that in ourCaffeine permeated society, the control group does not have much control.

However, the chemistry is obvious: high adenosine present during migraine, adenosine causes dilation of blood vessels, a condition of thought directly related to migraine and was once, they can cause, caffeine stimulates the increased production of and responsiveness to adenosine. There is no doubt that caffeine produces the conditions of the body that is very beneficial forMigraine headaches. So if we want to do everything in your power to suppress migraines would be wise to cut the drug completely from your diet. But slowly! Everyone knows that feels exactly like a headache from caffeine withdrawal.

Migraine Medications - The paradox of caffeine

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